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However, a growing body of evidence reveals a pronounced immunoinflammatory phenotype in OA, wherein macrophages, T/B lymphocytes, and inflammatory factors such as IL-1, TNF-, and IL-6 play a critical role in the local microenvironment (105)

One such toxin is formaldehyde, which is produced during several of the bodys metabolic processes

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Incretins are molecules associated with food intake-stimulation of insulin secretion from the pancreas