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Stability testing over 24 months under controlled conditions

Statements Author contributions NA and SS were involved in the development of the topic and initial drafts

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Insmed has announced plans to rapidly advance brensocatibs US marketing application, and if approved, it is expected to be marketed in the United States by mid-2025 ( 8.2 COPD COPD represents another therapeutic area with important application potential for DPP1 inhibitors ( Neutrophil-mediated inflammatory responses are considered to play key roles in COPD pathogenesis ( Currently, COPD treatment mainly includes bronchodilators, inhaled corticosteroids, and phosphodiesterase-4 inhibitors, but these therapeutic approaches have relatively limited effects on neutrophil-mediated inflammation (Wedzicha et al., 2016)