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Mitophagy in neurological disorders

Notably, hydrogen bonds, which account for the high affinity, are formed between DEHP and proteins due to the four hydrogen bond receptors of the carboxyl groups, including ASN-51 of HSP90AA1, ARG-24 of IL6, LYS-54 of MAPK1, GLN-20 of BCL2, GLN-20 of EP300, ARG-207 of CASP3, GLN-68 and THR-45 of ERBB2, LYS-87 of BCL2L1, and ARG-112 of GRB2

Vesugen is a synthetic bioregulatory tripeptide (3 amino acids, Khavinson peptide class)

Reviews flag this as an unresolved question, especially in patients with current or prior cancer (Sehgal et al., Pharmaceuticals, 2025)

J Nutr 2014;144:75864