Hepatic synthesis of glutathione and nutritional substrates, co-factors, and other nutrients that influence metabolism 5-Methyl-tetrahydrofolate (5MTHF), system alanineserinecysteine (ASC), cystathionine--synthase (CBS), cystathionine gamma-lyase (CGL), electrophile response element (EpRE), glutathione-S-transferase (GST), glutamate cysteine ligase (GCL), glutathione reductase (GRx), glutathione peroxidase (GPx), glutathione synthetase (GSx), hydrogen peroxide (H 2 O 2 ), Nuclear factor erythroid factor-2-related factor 2 (Nrf2), S-adenosylmethionine (SAMe), S-adenosylhomocysteine (SAH), tetrahydrofolate (THF), thioredoxin reductase 1 (TRR1), water (H 2 O), cystine/glutamate antiporter system (x c )
This recycling keeps methylation efficient and ensures methionine is always available for the next step
Why is that interesting
Int J Cell Biol, 2014
(9) Elena A Tukhovskaya, Alina M Ismailova, Elvira R Shaykhutdinova, Gulsara A Slashcheva, et al (2021) Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke Molecules, 2021 Aug 26, Volume 26 (Issue 17), Pages 5173
