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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

A pathophysiologic framework for the overlap of disorders of gut-brain interaction and the role of the gut microbiome

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Some people may notice changes within a few weeks, while others may require more consistent use over time

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