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Alcohol is principally metabolized by alcohol dehydrogenase in the liver after first pass via the hepatic portal vein, and during chronic alcohol consumption, by cytochrome P450 2E1 (CYP2E1) ( FIGURE 2 The first line of defense against microbial pathogens and debris in the respiratory system is the physical barriers and mucociliary transport

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Symptoms usually begin within the first week of quitting and can last up to two weeks or more, depending on the individual