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PLGA and other biodegradable carriers can readily be functionalized with GSH-cleavable linkers or redox-sensing moieties, providing clinically tractable routes to translate GSH-responsive designs into precision treatments [23]

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DOI: 10.1136/bmj.305.6855.693 Oldendorf WH (1971): Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection

Additionally, we investigate novel metabolic interventions, including lipase inhibitors, insulin therapy, and antioxidants, designed to address these metabolic disturbances and reduce the severity of the disease