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Nitric oxide synthase 2/inducible nitric oxide synthase (NOS2/iNOS) produces nitrous oxide subsequent to the stimulation of pro-inflammatory cytokines, which is an innate immune marker and has great significance in the diagnosis of psoriasis (133)

Most notably, AHK-Cu demonstrates preferential activity in hair follicle environments

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Curr Drug Metab 7:853872 Bolaos JP, Heales SJR, Peuchen S, Barker JE, Land JM, Clark JB (1996) Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione