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Additionally, when adjusted for confounding factors, the odds of hyperuricemia increased as smoking duration, smoking intensity, and cumulative dose increased in females (all p for trend 0.004)

They also provide COAs (Certificate of Authenticity) that you can examine prior to purchasing

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This may lead to more acne, taking longer to heal from skin cuts or conditions, and even acne scarring

For the study, the researchers noted that they measured nicotine concentration in the rodents after exposing them to an equal numbers of puffs of Juul, another e-cigarette, a regular cigarette and clean air