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4:389-398 (2013) Hajar-Azhari S, Wan-Mohtar W, Ab Kadir S, Rahim MHA, Saari N

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Specifically, GHK-Cu was found to be least possible to cause skin irritation, while CuCl 2 and Cu(OAc) 2 were found to induce the expression of various skin irritation biomarkers, i.e., IL-1, IL-8, FOSL1, and HSPA1A

Suffice to say, all the vitamins and minerals in this supplement are slightly less than the maximum daily intake values