[PubMed: 15274096] Zucker AN, Harrell ZA, Miner-Rubino K, Stewart AJ, Pomerleau CS, Boyd CJ
Available at: (Accessed November 23, 2022) 25
Nicotine, particularly in those first few cigarettes, increases the activity of dopamine, a chemical in the brain that elicits pleasurable sensations
Retrieved June 26, 2017
The health and economic cost of tobacco According to WHO: The tobacco epidemic is one of the biggest public health threats the world has ever faced, responsible for over 7 million deaths annually, as well as disability and long-term suffering from tobacco-related diseases. Additionally, a study by the organisation found that approximately 80% of the 1.3 billion tobacco users worldwide live in low- and middle-income countries, where the burden of tobacco-related illness and deaths is heaviest