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The plant NADPH oxidase RBOHD mediates rapid systemic signaling in response to diverse stimuli

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Moreover, GSH increase has been positively correlated with HepG2 cell growth: inhibiting or increasing cellular GSH, DNA synthesis and cell proliferation were, respectively, reduced or improved [319]

This reaction is catalyzed by the enzyme gamma-glutamyl-cysteine synthetase, which is encoded by the gene gshA

Their vesicular structure enables encapsulation of both hydrophilic and lipophilic drugs, with enhanced dermal penetration and sustained drug release [136]