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Thats why frequency often becomes part of protocol planning

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On the other hand, short-term studies showed no significant impact on blood sugar levels from either furosemide or bumetanide in both healthy individuals and patients with T2D (Kaldor et al., 1975)

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MiR-25 is overexpressed in both keratinocytes and melanocytes in response to oxidative stress, which decreases the activity of antioxidant enzymes and impairs melanosome transport, leading to redox imbalance [51]