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This suggests that the compromised mitochondrial activity due to CoA deficiency necessitates cytoplasmic futile creatine cycling for thermogenesis

Crossref Yokota SI, Amano KI, Nishitani C, Ariki S, Kuroki Y, Fujii N

Six cysteine residues that are in general associated with the antimicrobial activity of the peptide are conserved between the equine, porcine and bovine primary structure

Since DFO is membrane impermeable and accumulates in lysosomes 18 , we believe that it protects the cells against ferroptosis by chelating lysosomal iron as described previously 47