Vitamin B12 There is four types of parenteral Vitamin B12 available: Cyanocobalamin 100 mcg/ml and 1000 mcg/ml best used as IM to prevent rapid loss via kidneys Hydroxycobalamin IM (compounded 1000 mcg/ml or more) known as long acting B12 (binds better to plasma proteins than cyanocobalamin) Methylcobalamin IV (compounded 1000 mcg or more up to 5000 mcg/ml) Adenosylcobalamin IV Common dose is 1000 mcg IM or IV Vitamin B12 as hydroxycobalamin is synthesized exclusively by microorganisms and is found in the liver of animals bound to protein as methylcobalamin = metabolically active form of Vitamin B12 Hydroxycobalamin is a chelator of cyanide and is used in cyanide poisoning Hydroxocobalamin is most generally used for vitamin B12 replacement therapy and is considered the drug of choice for vitamin B12 deficiency by the Martindale Extra Pharmacopoeia (Sweetman, 2002) and the World Health Organization (WHO) Model List of Essential Drugs
In rare cases, patients can experience severe allergic reactions that need immediate medical attention
Green Relief Healths proprietary Skinny Booster contains : MIC Complex (25mg methionine, 50mg inositol, 50mg choline), Vitamin B12 (1000mcg methylcobalamin), L-Carnitine (100mg for enhanced fat transport), and B-Complex (B1, B2, B6 for complete energy support)
PMID 15652195 Mahler HC, Friess W, Grauschopf U, Kiese S
Use bacteriostatic water rather than sterile water to enable multi-dose use from single vials
