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doi: 10.1038/ni.2833 79 GrzesKMSaninDEKabatAMStanczakMAEdwards-HicksJMatsushitaMet al

[9] The domain containing the active site exhibits interesting properties of specificity

[13] Most mammalian isoenzymes have affinity for the substrate 1-chloro-2,4-dinitrobenzene, and spectrophotometric assays utilising this substrate are commonly used to report GST activity

Supplementation with DHO or OA(substrates and products of DHODH) attenuated and enhanced GPX4-induced iron death, respectively, especially in cancer cells with low GPX4 expression