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Understanding the roles and interventions of the GSH system, as well as its connection with ferroptosis, may favor the advancement of more effective therapies to prevent myocardial injury (summarized in Fig

Many thiol-based ATs may be poorly absorbed by cells, as seen again in the case of glutathione (Tsai et al., 2024)

Ultrastructural bases for metabolically linked mechanical activity in mitochondria

2 Additionally, tumor cells generally have heightened expression of GST, providing ideal conditions for GST-activated prodrugs

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