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In neurodegenerative diseases, inflammation may be triggered by the accumulation of aggregates or modified proteins, which could also be considered DAMPs [7]

Mitochondrial implication in apoptosis

TABLE 1 A category of drug-induced hyperpigmentation and their pathogenesis

Critical knowledge gaps continue to impede the development of more effective interventions

The IF1-P group had a significant increase in abundance of Ruminococcaceae Incertae Sedis and Eubacterium fissicatena group ( q 0.007), while the IF2-P group had a significant increase in abundance of Ruminococcaceae Incertae Sedis and a decrease in Eubacterium ventriosum group ( q 0.005)