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International Journal of Molecular Sciences, 2023;24(6), 5344.5 Klubo-Gwiezdzinska J, Wartofsky L

246 Sepsis often triggers a sepsis-associated encephalopathy (SAE) which presents itself with wide symptomatology including reduced attention, disrupted sleep-wakefulness balance, impaired speech and orientation, deficient leaning and memory, numerous perception disorders, focal neurological deficits, seizures, and, in terminal stages, coma

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However, the disruption of any of the above signalling pathways can induce apoptosis

They detected such cells in 8 of 11 patients diagnosed with MS (73%), versus 2 of 28 controls (7%), comprising normal persons and patients with non-MS inflammatory demyelinative diseases