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Experts highlighted the need for healthcare education on recognizing B12 deficiency symptoms and suggested targeted prophylactic supplementation for high-risk groups

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Since the body cannot produce B12 on its own, it must be obtained through diet or supplements

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In 2009, a double-blind randomised-controlled trial (RCT) found significant reductions in duration of outbreaks, the number of ulcers and the level of pain in those on B12, 1000 g per day sublingually (form not reported), regardless of B12 level