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Virginia is also the easiest entry point for adult smokers who found full American blends too heavy in the past, or for anyone who currently smokes an additive-free cigarette built on air-cured Virginia

As a result, this design has gained immense popularity, as is to be expected

We identified three outcomes with a 4-star association with smoking: COPD (72% increase in risk based on the BPRF, 0.54 ROS), lower respiratory tract infection (54%, 0.43) and pancreatic cancer (52%, 0.42)

However, actual equivalence can vary based on individual puff frequency and inhalation depth