First identified in 1977 from cerebral venous blood of rabbits during electrically induced sleep by Swiss researchers Schoenenberger and Monnier, DSIP has since been studied for its role in sleep architecture regulation, stress response modulation, and neuroendocrine activity
Refrigeration slows this conversion, maintaining effective preservative concentration closer to the 0.9% starting level through the 28-day window
At 20C, for example, 177 g of NaI, 91.2 g of NaBr, 35.9 g of NaCl, and only 4.1 g of NaF dissolve in 100 g of water
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doi: 10.1021/acs.chemrev.0c01332 61 PlachMSchubertT