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Direct human clinical trial evidence

The broader picture is one in which MOTS-c addresses a gap that many other longevity interventions leave unfilled: the mitochondrial signaling decline that is simultaneously a cause and consequence of metabolic aging

This accumulating evidence, while predominantly from animal models and in vitro experiments, encourages further investigation

The medium used to maintain the pellet was full chondrogenic medium (CM) consisted of DMEM (Gibco), 2 anti-anti (Gibco), 10 g/ml ITS (Thermo Fisher Scientific), 0.1 M Dexamethasone (Sigma-Aldrich, St

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