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Ethics declarations Conflict of interest Sun-Ki Kim, Managing Editor of Food Science and Biotechnology , was not involved in the editorial consideration of this manuscript

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The redox effects of GSH or other thiol agents can be assessed by the use of irreversible thiol alkylating agents such as N-ethyl maleimide (NEM) which would form covalent bonds with cysteine residues and prevent further modification of these sites as has been analyzed in modulation of GABA- and glycine-evoked currents in rat retinal ganglion cells (24)

The methylation cycle is an important part of glutathione production

Cytochrome P450 Enzyme Mediated Herbal Drug Interactions (Part 1). EXCLI Journal, vol