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Shown to boost glutathione levels in ethanol-induced rats, it was discovered that milk thistle could actually help protect the liver from toxicity in the presence of alcohol consumption

What could also result from this synergic mix is improved calcium uptake , given that vitamin D is considered the key factor in this process

Wang G, Bonkovsky HL, de Lemos A, Burczynski FJ (2015) Recent insights into the biological functions of liver fatty acid binding protein 1

Here's the mechanism: the enzyme ALDH2 (aldehyde dehydrogenase 2) oxidises acetaldehyde into acetic acid, but this process requires adequate glutathione reserves to neutralise reactive oxygen species (ROS) generated during the reaction

Ammoniaand its associated nitrogenis a toxic byproduct that requires activation of the urea cycle for homeostasis and prevention of ammonia toxicity