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doi: 10.1101/2024.09.19.613992 60

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Elevated iron levels are also linked to oxidative stress and ferroptosis, a programmed cell death dependent on intracellular ferrous iron and impaired antioxidant defense systems (Ward et al., 2022)

Lower Inflammatory Load : Supplemented patients recorded significant drops in pro-inflammatory cytokines that sustain chronic immune exhaustion in diabetic subjects

Lipoic acid prevented NOX-induced superoxide production in a rat model of cerebral ischemia and limited infarct volume and neurological deficiencies through upregulating the insulin-phosphatidylinositide-3 kinase (PI3K)-protein kinase B (PKB/Akt) signaling pathway (40)