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In preclinical studies, BPC-157 has been shown to enhance results by supporting the formation of new blood vessels (angiogenesis), improving blood flow, and increasing nitric oxide production, all of which contribute to overall performance and recovery

Additionally, reactive oxygen species (ROS), secreted in large amounts by activated microglia, can activate the Rho-kinase pathway, leading to pericyte contraction and inhibition of vasodilation, thus promoting vasoconstriction (Hartmann et al., 2021)

Liu, D., Wu, D., Wang, R., Shi, J., & Niu, F

If they diminish noticeably, the pituitary may be desensitizing, and a break is warranted