Extramedullary hematopoiesis involves the liver, spleen, and lymph nodes, and in extreme cases produces extraosseous masses in the thorax, abdomen, and pelvis
For patients who are deficient, we offer vitamin B12 injections as an effective treatment option
W.LuW.et al
This is possible due to the KEAP1/Nrf2 systems ability to be activated by ROS via oxidation of specific cysteine residues of KEAP1 protein
doi: 10.3389/fphar.2020.590855 Received 03 August 2020 Accepted 18 September 2020 Published 15 October 2020 Volume 11 - 2020 Edited by Efstratios Stratikos, National Centre of Scientific Research Demokritos, Greece Reviewed by Marcin Poreba, Wrocaw University of Science and Technology, Poland Akira Hattori, Kyoto University, Japan Updates Copyright 2020 Hallberg and Larhed