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The articles were collected, organized, and sorted using the Covidence software (Melbourne, Australia) for systematic review

Even if the pathophysiology of both conditions is not fully elucidated and not identical, the role of an impaired intestinal barrier function and altered microbiota in the pathogenesis and progression of chronic liver disease is increasingly recognized as a key player

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High blood sugar and obesity contribute to inflammation in fat tissue

In 2010, researchers used the Broad Institute's Connectivity Map to identify potential treatments for aggressive metastatic colon cancer