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Cellular senescence and tumor suppressor gene p16

PMID: 27975173

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Consequently, the accumulated NAPQI binds covalently to the cysteine, methionine, tyrosine, and tryptophan residues of various proteins, forming NAPQI-protein adducts within the cell that disrupt normal physiological protein functions

Safety Profile Recognized by the Cosmetic Ingredient Review (CIR) as safe INCI: Copper Tripeptide-1 CAS: 49557-75-7 Molecular Formula: C14H24N6O4 Used correctly, GHK-Cu is gentle enough for long-term daily application , even for sensitive and menopausal skin