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By targeting and inhibiting NNMT, it regulates adipose tissue physiology from multiple dimensions and serves as an important tool for dissecting the molecular mechanisms of adipose metabolism

Local microbial axes between adjacent organs The inter-organ axes described above operate primarily through systemic dissemination of microbial-derived signals via the portal circulation and peripheral bloodstream, with the gutliver axis serving as the central hub

The ability of sulforaphane (glucoraphanin-derived isothiocyanate) to reduce oxidative stress in different settings is linked to activation of the nuclear factor E2-related factor 2 (Nrf2)-dependent pathway

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