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The study used 20 mg/kg SC three times daily in mice

PMC6163457 WebMD

Mood changes such as irritability, depression, or anxiety, as well as numbness or tingling in the hands and feet, can also be linked to low B12 levels

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Clinical studies confirm that chronic treatment with AOD9604 showed no adverse effect on insulin sensitivity, making it a metabolically selective approach to body composition optimization under medical supervision