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This synthetic variant exhibits reduced binding to IGF binding proteins, allowing enhanced bioavailability and systemic activity [2]

Inhibition of mast cell activation could be used as an initial adjuvant therapy to treat hypoxia-ischemia, ischemic stroke, and ICH in new-borns and adults (Strbian et al., 2009)

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Kirazli O, Ozkan M, Verimli U, Gulhan R, Arman A, and Sehirli US

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Rather than the KAR receptor, ShHTL1 is likely to be the receptor for KL, an endogenous signaling molecule that shares structural similarity with KAR, in particular the butenolide ring