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Only a limited number of patients who were allergic to allopurinol have been studied to date, but the drug was tolerated in those patients

Huang et al., 2024

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ACS Nano 15 , 1946819479 (2021)

its strongest evidence base is in cardiac muscle, skeletal muscle, and skin wound healing models The combination is studied to investigate whether the two pathways exhibit additive or synergistic effects across tissue repair endpoints a question that would be difficult to study with either compound alone