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While the distribution (measured in unit body weight) of GSH in hearts skeletal muscle and brain is not as high as in other organs, the excretion of GSH via these organs is slower

While the second-order rate constants of PfGrx C88S and PfGrx C32S/C88S for GSSG are one order of magnitude higher than for bulky roGFP2(SSG), the rate constant for the glutathionylation of PfGrx C32S/C88S by GSSG is twice that with GSSCys (Table 1) 14