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Deng et al., 2023)

Conclusions from 67 Cu uptake and release measurements performed in hypothalamic slices by the presence of action potential blocker tetrodotoxin [231, 232] or determination of depolarization-induced copper release from nerve endings by AAS [225] raised the concept of copper signalling in the brain

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Inhibition of MAPK Signaling and Tau Hyperphosphorylation NAC has demonstrated the ability to inhibit MAPK signaling pathways and diminish tau hyperphosphorylation, revealing novel protective mechanisms that guard against neuronal injury [29]

Neurobiol Dis 2024:106520 Bedini A et al (2024) Industrial and academic approaches to the search for alternative melatonin receptor ligands: an historical survey