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This amino acid is also synthesized by adipocytes, liver, and lung, and after its release into the bloodstream, glutamine is transported to be metabolized in several tissues [2]

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For example, vactosertib, an orally bioavailable TGF- receptor kinase inhibitor, showed efficacy against multiple myeloma in preclinical models, either as a monotherapy or in combination with other treatments [343, 344], leading to the clinical assessment of vactosertib

Barber AJ