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In macrophages, reorganization of the actin cytoskeleton necessary for chemotaxis and phagocytosis requires MsrB1-dependent reduction of methionine-R-sulfoxide residues within actin (27)

Consistent with these findings, caspase-3/7 activity showed a modest, non-significant increase with MitoQ alone after 24h, but was elevated when MitoQ was combined with DPI

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