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Oxidative stress activates NUPR1 by both ER stress (METH [79] and H2O2 [80]) and non-ER stress pathways, NUPR1 regulates ferroptosis via iron metabolism, ROS homeostasis, and the GSH/GPX4 pathway [81, 82]

Microplastics increase tumorigenesis risk by inducing cellular genetic mutations and inflammatory responses (26), particularly in children and adolescents, microplastic exposure shows close correlation with brain tumor development, the toxicity of microplastics may affect the tumor microenvironment, promoting tumor cell proliferation and metastasis

[7] Vitamin B 12 activation Methyl-THF converts vitamin B 12 to methyl-B 12 (methylcobalamin)

Fluid retention and joint discomfort, a recurring effect of growth-hormone-axis stimulation across the secretagogues in this list

(a ) Study design during indirect calorimetry