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A 1984 publication reported observations involving people with narcolepsy

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The results were measured with 3D skin surface imaging, not subjective assessment: GHK-Cu reduced wrinkle volume by 55.8% compared to a control serum

Because the headline trial figures were measured at 26 and 68 weeks, community sources caution against judging response on a few weeks of data when the trial curves were still descending well past month six (Lau et al., 2021