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The l-citrulline vs l-arginine bioavailability comparison shows l-citrulline produces 2-3 times higher plasma arginine levels at equivalent doses

The peptide's development focused on enhancing hydrophobicity, decreasing hydrogen bonding potential, and increasing metabolic stability, resulting in a compound with an exceptionally long plasma half-life of approximately 335 minutes

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Gut 69 , 92102 (2020)