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The LKKTET(Q) motif binds G-actin, buffering monomers and regulating polymerization so cells can rapidly reorganize their cytoskeleton and move into injured tissue

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CGI-58 Mutations in CGI-58 (Comparative Gene Identification 58), also known as ABHD5 (alpha/beta-hydrolase domain-containing protein 5) have been found to be the cause of a rare autosomal recessive disease called Chanarin-Dorfman syndrome (CDS) (67)

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