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Its stability and apparent pleiotropic activity have po Mechanism of Action BPC-157 modulates angiogenic signaling pathways specifically through upregulation of vascular endothelial growth factor receptor-2 (VEGFR2) activity

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doi: 10.1016/j.physbeh.2018.10.013

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Administration of CB-1158 (a small molecule inhibitor of arginase) can slow tumor growth rates, block myeloid cell-mediated suppression of T-cell proliferation, and increase the number of tumor-infiltrating CD8 + T cells and NK cells in mouse models of multiple tumors