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Drug screening MAPS was performed as previously described 41

doi: 10.1073/pnas.78.11.6858

Glutathione conjugation plays a significant role in detoxifying reactive electrophilic compounds

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Research emphasizes the importance of the endocannabinoid system (ECS) in neurotrophic factor signaling during fetal CNS development, regulating synaptogenesis, axon growth, neuronal cell fate, migration, and proliferation, as well as neuroprotection mediated by CB1R and BDNF, preventing neuronal death, and the ECSs influence on dopaminergic systems (primarily through D2 receptors), GABAergic, and glutamatergic systems (163)