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As summarized above, there is a breakdown of the BBB in AD along with an increase in oxidative stress and inflammatory disfunction [112]

therefore, patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA WR

But at higher concentrations like 20mg/mL, 1 unit of dead space equals 200mcg, and 5 draws waste 1,000mcg (1mg), which is 5% of a 20mg vial

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