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Several signaling pathways contribute to malignant transformation, including oncogenic pathways (RAS, PI3K/Akt, Wnt/-catenin), anti-apoptotic Bcl-2 family activity, and epithelial-mesenchymal transition (EMT)/EMP-driven invasion and resistance (Kaloni et al

Nalle SC, Turner JR

10.3390/ijms22095010 4 AquilanoK.BaldelliS.CirioloM