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suggested that PTU therapy might be continued with caution in the presence of elevated liver transaminases, when no hyperbilirubinemia is present.15 However, regular monitoring of liver biochemistry has been suggested to allow discontinuation of PTU in suspected cases of hepatic injury.15,17 The diagnosis of PTU hepatotoxic effect should always be suspected in the patient receiving PTU therapy in whom clinical or biochemical evidence of acute hepatitis develops

[DOI] [PMC free article] [PubMed] [Google Scholar] 286.Hemil H

But even today, more than three decades after BPC-157 was first synthesized, a grand total of three human studies have been conducted, and none of them were the kind of large-scale human trial thats typically part of the traditional drug-approval process

So therefore, dont think

We can say that PRP has a high percentage of negative side effects in musculoskeletal regenerative therapies and sadly, a remaining unanswered question about the efficacy and safety of PRP ( hence the featured published manuscript.