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However, contradictory findings were obtained in a recent study which concluded that mutant TDP-43 A315T does not impair mitochondrial bioenergetics in vitro and in vivo (Kawamata et al., 2017)

In line, ETC complex protein levels were reduced in mutant FoB compared to controls (Supplementary Fig

Population pharmacokinetic-pharmacodynamic (PKPD) modelling to describe the effects of paracetamol and N -acetylcysteine on the International Normalised Ratio (INR)

Gottenberg JE, Brocq O, Perdriger A et al (2016) Non-TNF-targeted biologic vs a second anti-TNF drug to treat rheumatoid arthritis in patients with insufficient response to a first Anti-TNF drug: a randomized clinical trial

Nov 2012;35(2):137-149