Ethics statement The animal study was approved by Shanghai Ocean University Animal Ethics Committee
Cherry: Purified water, support diluent (vegetable glycerin), L-camitin base, acidulant (citric acid), color (beetroot red color E-162), aroma, preservatives (sodium benzoate and potassium sorbate), sweetener (sucralose) and vitamin B6 (pyridoxine hydrochloride)
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Preparation of NEM-derivatized cysteine and GSH internal standards The N-ethylmaleimide (NEM) derivatized isotope labeled [ 13 C 3 , 15 N]-cysteine-NEM and [ 13 C 2 , 15 N]-GSH-NEM were prepared by derivatizing the [ 13 C 3 , 15N]-cysteine and [ 13 C 2 , 15 N]-GSH standards with 50 mM NEM in 10 mM ammonium formate (pH = 7.0) at room temperature (30 min) as previously described 95
