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The cleanup costs the city an estimated 10 million annually , but the environmental toll is even worse: just one cigarette butt, with its 4,000 chemicals, can contaminate up to 500 liters of water

Statistics To determine the effect of moderators, a mixed-effects model was used, in which the unknown true effect, y i , is given by y i = 0 + 1 x i 1 + + p x i p + u i + e i , where x i p denotes the value of the p th moderator for the i th study, and p denotes the change in the average true effect for a one unit increase in x i p

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